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WIF1
Anti-WIF1 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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- Mouse Anti-WIF1 Monoclonal Antibody (VS7-0425-WR1128) (VS7-0425-WR1128)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC, ELISA
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- Mouse Anti-WIF1 Monoclonal Antibody (clone 1G5) (VS7-0425-WR1127)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Protein class
Cancer-related genes
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (Muller glia cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEK93, LHCN-M2, NTERA-2)
Interaction
Interacts with MYOC.
Molecular function
Developmental protein
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