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WIPI2

Anti-WIPI2 Products

Recombinant Mouse anti-Human WIPI2 Monoclonal antibody (3B3) (MOB-2162CT)
- Species Reactivity: Human
- Application: ICC/IF, IHC-Fr, IHC-P, IP, WB
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Rabbit Anti-WIPI2 Recombinant Antibody (clone DS3876AB) (MOR-3876)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids.

Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Late spermatids, Spermatocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with TECPR1 (PubMed:21575909). Interacts with ATG16L1 (PubMed:24954904, PubMed:28561066). Interacts with ATG5 (PubMed:24954904). Interacts with WIPI1 (PubMed:28561066). Interacts with WDR45 (PubMed:28561066). May interact with NUDC (PubMed:28561066). Interacts with ULK1 and RB1CC1 (PubMed:28890335).

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