ZNF277
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
Transcription factors
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts (via zinc-finger domains) with RPS2/40S ribosomal protein S2, perhaps as nascent RPS2 is synthesized during translation; the interaction is direct; the interaction is extra-ribosomal (PubMed:30530495). Interaction with RPS2 competes with the binding of RPS2 to protein arginine methyltransferase PRMT3 (PubMed:30530495). Interacts with Polycomb group (PcG) complex protein BMI1 (By similarity). May be part of a complex including at least ZNF277, BMI1 and RNF2/RING2 (By similarity).
DNA-binding

