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ZNRF2

May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Microglial cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC)

Cell line specificity

Low cell line specificity

Interaction

Interacts with UBE2N.

Molecular function

Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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