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Mouse Anti-acma Recombinant Antibody (clone 2506W0224) (VS-0625-FY329)
- Species Reactivity: Streptomyces galilaeus
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.

Background

Aklanonic acid methyl ester cyclase AcmA is an enzyme involved in the biosynthesis of aklavinone, a key intermediate in the production of anthracycline antibiotics like doxorubicin. AcmA catalyzes a crucial cyclization reaction in this pathway, contributing to the formation of the characteristic polycyclic structure of these potent anticancer agents. Its activity is vital for the production of these therapeutically important compounds.