codA

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For Research Use Only. Not For Clinical Use.


Background

Cytosine deaminase is an enzyme that catalyzes the deamination of cytosine to uracil. This enzyme is important in pyrimidine metabolism and is also a target for gene therapy in cancer, where it can be used to convert a prodrug, 5-fluorocytosine, into the cytotoxic agent 5-fluorouracil.
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