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E2F8

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For Research Use Only. Not For Clinical Use.


Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Erythroid cells, Gastric mucus-secreting cells, Squamous epithelial cells, Plasma cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Homodimer and heterodimer: mainly forms homodimers and, to a lesser extent, heterodimers with E2F8. Dimerization is important for DNA-binding. Interacts with HIF1A.

Molecular function

Activator, DNA-binding, Repressor

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