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IL17c

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For Research Use Only. Not For Clinical Use.


Background

The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells.
Predicted location

Secreted

Single cell type specificity

Group enriched (Basal respiratory cells, Club cells, Ionocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Binds to a heterodimer formed by IL17RA and IL17RE.

Molecular function

Cytokine

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