lpxA
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Loading...- Mouse Anti-lpxA Recombinant Antibody (clone 2506W0554) (VS-0625-FY659)
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- Species Reactivity: Helicobacter pylori (strain 700392/26695)
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
lpxA, or Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, is the first committed enzyme in lipid A biosynthesis in Gram-negative bacteria. It catalyzes the transfer of an R-3-hydroxymyristoyl group from acyl-ACP to UDP-N-acetylglucosamine. LpxA is crucial for the synthesis of lipid A, the endotoxic component of LPS, making it an attractive antibacterial target.