prfA
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Loading...- Mouse Anti-prfA Recombinant Antibody (clone 2506W0860) (VS-0625-FY965)
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- Species Reactivity: Listeria monocytogenes serovar 1/2a (strain BAA-679/EGD-e)
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
prfA, or Listeriolysin regulatory protein, is a transcriptional activator in Listeria monocytogenes that controls the expression of virulence genes, including those for listeriolysin O (LLO) and phospholipases. PrfA is crucial for the intracellular survival and dissemination of Listeria within the host, acting as a master regulator of virulence.

