prfA

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For Research Use Only. Not For Clinical Use.


Background

prfA, or Listeriolysin regulatory protein, is a transcriptional activator in Listeria monocytogenes that controls the expression of virulence genes, including those for listeriolysin O (LLO) and phospholipases. PrfA is crucial for the intracellular survival and dissemination of Listeria within the host, acting as a master regulator of virulence.
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