vatD

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For Research Use Only. Not For Clinical Use.


Background

vatD, or Streptogramin A acetyltransferase, is an enzyme that confers resistance to streptogramin A antibiotics. VatD catalyzes the acetylation of streptogramin A, rendering it inactive and preventing its binding to the bacterial ribosome. This enzyme is a significant mechanism of antibiotic resistance in Gram-positive bacteria.
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