10-FnIII scaffold protein anti-SARS N protein
CAT#: SFN-L020
The tenth fibronectin type III domain (10Fn3) that bound SARS N protein was isolated from the library using mRNA Display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=1.7 nM) for SARS N protein as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- 10-FnIII
- Origin
- Fibronectin
- Core Structure
- β-sandwich of 7 β-strands
- Variable Regions
- 2–3 Loops
- Target
- SARS N protein
- Species Reactivity
- SARS
- Expression Host
- E. coli
- Affinity Constant
- 1.7 nM
- Applications
- ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
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See other products for "N"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1231CT | Recombinant Mouse anti-Other N Monoclonal antibody (iNQW 44) | ELISA, ICC, IF |
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