10-FnIII scaffold protein anti-Human SUMO4
CAT#: SFN-L008
The tenth fibronectin type III domain (10Fn3) that bound SUMO4 was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=7 nM) for SUMO4 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- 10-FnIII
- Origin
- Fibronectin
- Core Structure
- β-sandwich of 7 β-strands
- Variable Regions
- 2–3 Loops
- Target
- SUMO4
- Species Reactivity
- Human
- Expression Host
- E. coli
- Affinity Constant
- 7 nM
- Applications
- ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
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See other products for "SUMO4"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3463 | Hi-Affi™ Recombinant Rabbit Anti-SUMO4 Monoclonal Antibody (DS3463AB) | WB, ICC, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1453-CN | Recombinant Rabbit Anti-SUMO4 Monoclonal Antibody (CBACN-539) | WB, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1034 | Rabbit Anti-SUMO4 Recombinant Antibody (VS3-WK1034) | WB, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7025 | Anti-SUMO4 Immunohistochemistry Kit | IHC |
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