The tenth fibronectin type III domain (10Fn3) that bound ySUMO was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity (Kd=5 nM) maturation, 10Fn3 variants were identified having affinities for ySUMO as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3463 | Hi-Affi™ Recombinant Rabbit Anti-SUMO4 Monoclonal Antibody (DS3463AB) | WB, ICC, IP, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1453-CN | Recombinant Rabbit Anti-SUMO4 Monoclonal Antibody (CBACN-539) | WB, IF, IP, FC | Rabbit IgG |
VS3-WK1034 | Rabbit Anti-SUMO4 Recombinant Antibody (VS3-WK1034) | WB, ICC, IF, IP, FC | Rabbit IgG |
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