10-FnIII scaffold protein anti-ySUMO (CAT#: SFN-L031)

The tenth fibronectin type III domain (10Fn3) that bound ySUMO was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity (Kd=5 nM) maturation, 10Fn3 variants were identified having affinities for ySUMO as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


Specific Inquiry
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Specifications

  • Scaffold Name
  • 10-FnIII
  • Origin
  • Fibronectin
  • Core Structure
  • β-sandwich of 7 β-strands
  • Variable Regions
  • 2–3 Loops
  • Target
  • ySUMO
  • Species Reactivity
  • yeast
  • Expression Host
  • BL21 (DE3) cells
  • Affinity Constant
  • 5 nM
  • Applications
  • ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study

Target

  • Alternative Names
  • Fibronectin; 10-FnIII; IDDM5; SMT3H4; SUMO-4; dJ281H8.4

Downloads

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Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3463 Hi-Affi™ Recombinant Rabbit Anti-SUMO4 Monoclonal Antibody (DS3463AB) WB, ICC, IP, FC IgG

Recombinant Antibody

CAT Product Name Application Type
MRO-1453-CN Recombinant Rabbit Anti-SUMO4 Monoclonal Antibody (CBACN-539) WB, IF, IP, FC Rabbit IgG
VS3-WK1034 Rabbit Anti-SUMO4 Recombinant Antibody (VS3-WK1034) WB, ICC, IF, IP, FC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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