APC-A*02:01/B-cell Translocation Gene 1 (TLWVDPYEV) MHC Tetramer (CAT#: MHC-LC683)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of B-cell Translocation Gene 1-derived peptide of TLWVDPYEV sequence covering 103-111 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5972/92_E5_2_selected.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000133639-BTG1
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- B-cell Translocation Gene 1
- Antigen Species
- Zaire ebolavirus
- Peptide
- TLWVDPYEV
- Range
- 103-111
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
- Alternative Names
- BTG1; BTG anti-proliferation factor 1; B-cell Translocation Gene 1; APRO2
- Gene ID
- 911829
- UniProt ID
- Q05320
Downloads
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MOB-1479MZ | Mouse Anti-BTG1 Recombinant Antibody (clone 3006D2b) | WB | Mouse IgG1 |
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