PE-A*02:01/B-cell Translocation Gene 1 (TLWVDPYEV) MHC Tetramer (CAT#: MHC-LC682)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of B-cell Translocation Gene 1-derived peptide of TLWVDPYEV sequence covering 103-111 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5972/92_E5_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5972/92_E5_2_selected.jpg
Figure 2 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000133639-BTG1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000133639-BTG1
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- B-cell Translocation Gene 1
- Antigen Species
- Zaire ebolavirus
- Peptide
- TLWVDPYEV
- Range
- 103-111
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
- Alternative Names
- BTG1; BTG anti-proliferation factor 1; B-cell Translocation Gene 1; APRO2
- Gene ID
- 911829
- UniProt ID
- Q05320
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1479MZ | Mouse Anti-BTG1 Recombinant Antibody (clone 3006D2b) | WB | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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