PE-A*02:01/B-cell Translocation Gene 1 (TLWVDPYEV) MHC Tetramer

CAT#: MHC-LC682

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of B-cell Translocation Gene 1-derived peptide of TLWVDPYEV sequence covering 103-111 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 RNA cell line category: Low cell line specificity

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • B-cell Translocation Gene 1
  • Antigen Species
  • Zaire ebolavirus
  • Peptide
  • TLWVDPYEV
  • Range
  • 103-111
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
  • Alternative Names
  • BTG1; BTG anti-proliferation factor 1; B-cell Translocation Gene 1; APRO2
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