APC-A*03:01/Human PLP1 (KLIETYFSK) MHC Tetramer

CAT#: MHC-LC1611

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PLP1-derived peptide of KLIETYFSK covering 45-53 and A*03:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • A*03:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • PLP1
  • Antigen Species
  • Human
  • Peptide
  • KLIETYFSK
  • Range
  • 45-53
  • Conjugate
  • APC

Target

  • Antigen Introduction
  • This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
  • Alternative Names
  • PLP1; proteolipid protein 1; PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20
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