APC-A*03:01/Human PLP1 (KLIETYFSK) MHC Tetramer (CAT#: MHC-LC1611)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PLP1-derived peptide of KLIETYFSK covering 45-53 and A*03:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- A*03:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- PLP1
- Antigen Species
- Human
- Peptide
- KLIETYFSK
- Range
- 45-53
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
- Alternative Names
- PLP1; proteolipid protein 1; PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20
- Gene ID
- 5354
- UniProt ID
- P60201
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