DRB1*03:01/Human PLP (RQIFGDYKTTIC) MHC Monomer (CAT#: MHC-YF110)
This product is a MHC monomer of biotinylated peptide/MHC complex composed PLP-derived peptide of RQIFGDYKTTIC sequence covering 98-109 and DRB1*03:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- DRB1*03:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- PLP
- Antigen Species
- Human
- Peptide
- RQIFGDYKTTIC
- Range
- 98-109
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
- Alternative Names
- PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20
- Gene ID
- 5354
- UniProt ID
- P60201
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For Research Use Only. Not For Clinical Use.
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