APC-B*07:02/Human POLR2A (TPQSNRPVM) MHC Tetramer (CAT#: MHC-LC2085)

• Allele
• B*07:02

• Class
• Class I

• MHC Species
• Human

• Antigen
• POLR2A

• Antigen Species
• Human

• Peptide
• TPQSNRPVM

• Range
• 527-535

• Conjugate
• APC

• Application
• FCM

• Antigen Introduction
• This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

• Alternative Names
• POLR2A; DNA-directed RNA polymerase II subunit RPB1; RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; RpIILS; hsRPB1; hRPB220

• Gene ID
• 5430

• UniProt ID
• P24928

Select a product category from the dropdown menu below to view related products.