APC-B*44:03/Human ABCD3 (EEYLQAFTY) MHC Tetramer
CAT#: MHC-LC1488
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of ABCD3-derived peptide of EEYLQAFTY covering 164-172 and B*44:03 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32026/if_selected.jpg
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Specifications
- Allele
- B*44:03
- Class
- Class I
- MHC Species
- Human
- Antigen
- ABCD3
- Antigen Species
- Human
- Peptide
- EEYLQAFTY
- Range
- 164-172
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Alternative Names
- ZWS2; ABC43; CBAS5; PMP70; PXMP1; ABCD3; ATP binding cassette subfamily D member 3
- Gene ID
- 5825
- UniProt ID
- P28288
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| MOR-0014 | Hi-Affi™ Rabbit Anti-ABCD3 Recombinant Antibody (clone DS14AB) | WB, ICC, FC | Rabbit IgG |
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