APC-B-FIV/Gallus gallus LCP2 (VIFPAKSL) MHC Tetramer (CAT#: MHC-LC1002)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LCP2-derived peptide of VIFPAKSL covering 159-166 and B-FIV molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human lymph node
(High expression.. RNA expression: 77.5 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_7_8_val_selected.jpg
(High expression.. RNA expression: 77.5 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_7_8_val_selected.jpg
Figure 2 IHC staining of human skeletal muscle
(Low expression.. RNA expression: 3.2 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_2_6_val_selected.jpg
(Low expression.. RNA expression: 3.2 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_2_6_val_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_9_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_9_5.jpg
Figure 4 Colon
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_3.jpg
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_3.jpg
Figure 5 Kidney
(Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_5.jpg
(Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_5.jpg
Figure 6 Testis
(Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_5_6.jpg
(Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_5_6.jpg
Figure 7 Bone marrow
(Hematopoietic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4574/11503_B_4_4.jpg
(Hematopoietic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4574/11503_B_4_4.jpg
Figure 8 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, Karpas-707, MOLT-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000043462-LCP2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000043462-LCP2
Specifications
- Allele
- B-FIV
- Class
- Class I
- MHC Species
- Chicken
- Antigen
- SLP-76
- Antigen Species
- Gallus gallus
- Peptide
- VIFPAKSL
- Range
- 159-166
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability.
- Alternative Names
- LCP2; lymphocyte cytosolic protein 2; SLP76
- Gene ID
- 395438
- UniProt ID
- Q9DG07
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| MOB-2280CT | Recombinant Mouse anti-Human LCP2 Monoclonal antibody (ED28) | WB, IHC-P |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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