APC-B-FIV/Gallus gallus LCP2 (VIFPAKSL) MHC Tetramer

Name: APC-B-FIV/Gallus gallus LCP2 (VIFPAKSL) MHC Tetramer
SKU: MHC-LC1002
Rating: 5 (1 reviews)

CAT#: MHC-LC1002

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LCP2-derived peptide of VIFPAKSL covering 159-166 and B-FIV molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression

Normal Tissue Figure 1 IHC staining of human lymph node

High expression.. RNA expression: 77.5 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_7_8_val_selected.jpg

Normal Tissue Figure 2 IHC staining of human skeletal muscle

Low expression.. RNA expression: 3.2 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_2_6_val_selected.jpg

Normal Tissue Figure 3 Cerebral cortex

Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_9_5.jpg

Normal Tissue Figure 4 Colon

Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_3.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_5.jpg

Normal Tissue Figure 6 Testis

Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_5_6.jpg

Normal Tissue Figure 7 Bone marrow

Hematopoietic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4574/11503_B_4_4.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, Karpas-707, MOLT-4, THP-1, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000043462-LCP2

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Specifications

Allele
B-FIV

Class
Class I

MHC Species
Chicken

Antigen
SLP-76

Antigen Species
Gallus gallus

Peptide
VIFPAKSL

Range
159-166

Conjugate
APC

Application
FCM

Target

Antigen Introduction
This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability.

Alternative Names
LCP2; lymphocyte cytosolic protein 2; SLP76

Gene ID
395438

UniProt ID
Q9DG07

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Datasheet

Datasheet - MHC-LC1002.pdf

MSDS

MSDS - MHC-LC1002.pdf

COA

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CAT	Product Name	Application	Type
MHC-LC1001	PE-B-FIV/Gallus gallus LCP2 (VIFPAKSL) MHC Tetramer	FCM
MHC-LC1003	BV421-B-FIV/Gallus gallus LCP2 (VIFPAKSL) MHC Tetramer	FCM

CAT	Product Name	Application	Type
MOR-2027	Hi-Affi™ Recombinant Rabbit Anti-LCP2 Monoclonal Antibody (DS2027AB)	FC, WB	IgG

CAT	Product Name	Application	Type
VS-0225-XY158	CytoStream™ Mouse Anti-LCP2 Recombinant Antibody (VS-0225-XY158)	FC	Mouse IgG2a, kappa

CAT	Product Name	Application	Type
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