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    PE-B-FIV/Gallus gallus LCP2 (VIFPAKSL) MHC Tetramer (CAT#: MHC-LC1001)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LCP2-derived peptide of VIFPAKSL covering 159-166 and B-FIV molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

    Specific Inquiry
    • Size:
    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human lymph node
    Figure 1 IHC staining of human lymph node
    (High expression.. RNA expression: 77.5 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_7_8_val_selected.jpg
    Figure 2 IHC staining of human skeletal muscle
    Figure 2 IHC staining of human skeletal muscle
    (Low expression.. RNA expression: 3.2 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_2_6_val_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_B_9_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_3.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Elongated or late spermatids
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Spermatogonia cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36396/85475_A_5_6.jpg
    Figure 7 Bone marrow
    Figure 7 Bone marrow
    (Hematopoietic cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4574/11503_B_4_4.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, Karpas-707, MOLT-4, THP-1, U-937)
    Figure 8 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, Karpas-707, MOLT-4, THP-1, U-937)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000043462-LCP2

    Specifications

    • Allele
    • B-FIV
    • Class
    • Class I
    • MHC Species
    • Chicken
    • Antigen
    • SLP-76
    • Antigen Species
    • Gallus gallus
    • Peptide
    • VIFPAKSL
    • Range
    • 159-166
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability.
    • Alternative Names
    • LCP2; lymphocyte cytosolic protein 2; SLP76

    Downloads

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    Please select product type
    IgG Antibody Products MHC Tetramer Products for Other Applications Rabbit Monoclonal Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    MOB-2280CT Recombinant Mouse anti-Human LCP2 Monoclonal antibody (ED28) WB, IHC-P

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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