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    APC-DRB1*11:01/Human CLIP (PVSKMRMATPLLMQA) MHC Tetramer (CAT#: MHC-LC643)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CLIP-derived peptide of PVSKMRMATPLLMQA sequence covering 103-117 and HLA-DRB1*11:01 molecule. The pMHC tetramer recognizes human CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
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    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line SiHa
    Figure 1 IF staining of human cell line SiHa
    (Immunofluorescent staining of human cell line SiHa shows localization to microtubule ends.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human placenta
    Figure 2 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/ihc_selected.jpg
    Figure 3 IHC staining of human prostate
    Figure 3 IHC staining of human prostate
    (Immunohistochemical staining of human prostate shows strong cytoplasmic and nuclear positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4399/ihc_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_B_9_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_9_3.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_7_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_4_6.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26678/56427_A_7_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Low cell line specificity
    Figure 9 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130779-CLIP1

    Specifications

    • Allele
    • DRB1*11:01
    • Class
    • Class II
    • MHC Species
    • Human
    • Antigen
    • CLIP
    • Antigen Species
    • Human
    • Peptide
    • PVSKMRMATPLLMQA
    • Range
    • 103-117
    • Conjugate
    • APC
    • Application
    • FCM

    Target

    • Antigen Introduction
    • The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.
    • Alternative Names
    • CLIP1; CAP-Gly domain containing linker protein 1; RSN; CLIP; CYLN1; CLIP170; CLIP-170

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    MOB-2359CT Recombinant Mouse anti-Human CLIP1 Monoclonal antibody (BG2I2) ICC/IF, WB, IHC-P
    VS3-FY394 Recombinant Rabbit Anti-CLIP1 Antibody (clone R07-1F3) WB, IHC-F, IHC-P, ICC, IF, IP Rabbit IgG

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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