APC-H-2Db/Human PSA (HCIRNKSVIL) MHC Tetramer (CAT#: MHC-LC217)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of hPSA-derived peptide of HCIRNKSVIL sequence covering 65-74 and H-2Db molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/764/2093_A_1_5_selected.jpg
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/764/2093_A_1_5_selected.jpg
Figure 2 RNA cell line category: Group enriched (BEWO, NB-4, RPMI-8226, SH-SY5Y, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000142515-KLK3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000142515-KLK3
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- PSA
- Antigen Species
- Human
- Peptide
- HCIRNKSVIL
- Range
- 65-74
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
- Alternative Names
- KLK3; kallikrein related peptidase 3; APS; PSA; hK3; KLK2A1
- Gene ID
- 354
- UniProt ID
- P07288
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-603-F(E) | Recombinant Anti-human KLK3 Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| MHH-603-F(E) | Recombinant Human Anti-human KLK3 Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| PFBL-256 | Mouse Anti-KLK3 Recombinant Antibody Fab Fragment (PFBL-256) | WB, IHC, FuncS | Mouse Fab |
| PFBL-678 | Mouse Anti-KLK3 Recombinant Antibody; Fab Fragment (PFBL-678) | WB, FuncS | Mouse Fab |
| FAMAB-0159JF-F(E) | Mouse Anti-KLK3 Recombinant Antibody (clone 1L123H-f); Fab Fragment | IF, ELISA, FuncS | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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