APC-H-2Kb/Trypanosoma cruzi Trans-sialidase (TcTS) (ANYKFTLV) MHC Tetramer
CAT#: MHC-LC632
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Trypanosoma cruzi-derived peptide of ANYKFTLV sequence covering 380-387 and H-2Kb molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Kb
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Trypanosoma cruzi Trans-sialidase (TcTS)
- Antigen Species
- Trypanosoma cruzi
- Peptide
- ANYKFTLV
- Range
- 380-387
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Trypanosoma cruzi is a species of parasitic euglenoids. Amongst the protozoa, the trypanosomes characteristically bore tissue in another organism and feed on blood (primarily) and also lymph. This behaviour causes disease or the likelihood of disease that varies with the organism: for example, trypanosomiasis in humans (Chagas disease in South America ), dourine and surra in horses, and a brucellosis-like disease in cattle. Parasites need a host body and the haematophagous insect triatomine (descriptions "assassin bug", "cone-nose bug", and "kissing bug") is the major vector in accord with a mechanism of infection. The triatomine likes the nests of vertebrate animals for shelter, where it bites and sucks blood for food. Individual triatomines infected with protozoa from other contact with animals transmit trypanosomes when the triatomine deposits its faeces on the host's skin surface and then bites. Penetration of the infected faeces is further facilitated by the scratching of the bite area by the human or animal host.
- Alternative Names
- T. cruzi TcTS; Trypanosoma cruzi Trans-sialidase
- Gene ID
- 3537653
- UniProt ID
- Q4CZ79
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC631 | PE-H-2Kb/Trypanosoma cruzi Trans-sialidase (TcTS) (ANYKFTLV) MHC Tetramer | FCM |
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