APC-H-2Kd/Influenza A virus HA (LYQNVGTYV) MHC Tetramer
CAT#: MHC-LC552
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Influenza-derived peptide of LYQNVGTYV sequence covering 204-212 and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Kd
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Influenza A virus HA
- Antigen Species
- Influenza A virus
- Peptide
- LYQNVGTYV
- Range
- 204-212
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics.
- Alternative Names
- Influenza A virus hemagglutinin; Influenza A virus HA
- Gene ID
- 3654620
- UniProt ID
- Q9Q0U6
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Specific Flu HA Detection
This APC-conjugated tetramer was effective for identifying mouse CD8 T cells specific to the Influenza A virus HA peptide LYQNVGTYV. The H-2Kd restriction was accurate, and the staining was clear in our viral models.
Reliable Influenza Reagent
We used this product to analyze T cell responses to the hemagglutinin 204-212 epitope. The tetramer performed consistently, allowing us to quantify antigen-specific cells and track the immune response to influenza.
Q&As
-
Which Influenza A epitope is recognized by this tetramer?
A: This tetramer recognizes the Influenza A virus Hemagglutinin (HA) epitope with the sequence LYQNVGTYV (amino acids 204-212). It is presented by the mouse H-2Kd molecule.
-
Can this product be used for flow cytometry?
A: Yes, this APC-conjugated tetramer is validated for use in flow cytometry (FCM). It allows researchers to quantify and analyze individual antigen-specific mouse CD8 T cells.
View the frequently asked questions answered by Creative Biolabs Support.
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Datasheet
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