APC-HLA-A2/Human CDC25B (GLLGSPVRA) MHC Tetramer
CAT#: MHC-LC1443
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CDC25B-derived peptide of GLLGSPVRA covering 38-46 and HLA-A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38893/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75215/1746_E6_3_cr5804b5837ad3c_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38893/113928_A_8_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38893/113928_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38893/113928_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38893/113928_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101224-CDC25B
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Specifications
- Allele
- HLA-A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- CDC25B
- Antigen Species
- Human
- Peptide
- GLLGSPVRA
- Range
- 38-46
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
- Alternative Names
- CDC25B; cell division cycle 25B
- Gene ID
- 994
- UniProt ID
- P30305
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Datasheet
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See other products for "CDC25B"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2468MZ | Recombinant Mouse Anti-Human CDC25B Antibody (clone EDT-273) | IHC-Fr, IHC-P, IP | Mouse antibody |
| MRO-0325-CN | Rabbit Anti-CDC25B Recombinant Antibody (clone CBACN-126) | WB, IP | Rabbit IgG |
| ZG-0602J | Rabbit Anti-CDC25B Recombinant Antibody (clone 3D6) | ELISA | Rabbit IgG |
| VS3-CJ866 | Rabbit Anti-CDC25B Recombinant Antibody (VS3-CJ866) | WB, IP | Rabbit IgG |
| VS13-YC184 | Rabbit Anti-CDC25B Recombinant Antibody (VS13-YC184) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0109MZ | Chicken Anti-CDC25b Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1442 | PE-HLA-A2/Human CDC25B (GLLGSPVRA) MHC Tetramer | FCM | |
| MHC-LC1444 | BV421-HLA-A2/Human CDC25B (GLLGSPVRA) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0600 | Hi-Affi™ Rabbit Anti-CDC25B Recombinant Antibody (clone DS600AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY382 | Anti-CDC25B Immunohistochemistry Kit | IHC | |
| VS-0525-XY1258 | Anti-Human CDC25B Immunohistochemistry Kit | IHC |
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