PE-HLA-A2/Human CDC25B (GLLGSPVRA) MHC Tetramer (CAT#: MHC-LC1442)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CDC25B-derived peptide of GLLGSPVRA covering 38-46 and HLA-A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specific Inquiry
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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

Peptide Sequence *:
Allele Requested *:
Antigen Species:
Antigen Molecule:
Sequence Position:
Form Requested *:
Conjugation *:
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Comments:

Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • HLA-A2
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • CDC25B
  • Antigen Species
  • Human
  • Peptide
  • GLLGSPVRA
  • Range
  • 38-46
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
  • Alternative Names
  • CDC25B; cell division cycle 25B

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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