Mouse Anti-α4β7 Recombinant Antibody (clone mAb ACT-1); Fab Fragment
CAT#: PFBL-739
Recombinant Mouse Antibody (fab ACT-1) is capable of binding to α4β7.
Specifications
- Immunogen
- Human Alpha-4 beta-7
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse Fab
- Specificity
- Human α4β7
- Species Reactivity
- Human
- Clone
- mAb ACT-1
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Alpha-4 beta-7; α4β7; integrin
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Precision Tool for Immune Mapping
This Fab fragment's ability to precisely label α4β7 integrins in flow cytometry allows detailed mapping of lymphocyte trafficking. It offers high purity and specificity, which are essential for our investigations into immune cell behavior in gut tissues.
Enhanced Immune Research Insights
Utilizing this Fab fragment, we've gained enhanced insights into the roles of α4β7 in immune regulation. Its excellent tissue penetration and binding robustness are critical attributes for our cellular and molecular studies.
Q&As
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How does this product contribute to inflammation research?
A: By targeting and elucidating the functions of α4β7, researchers can explore pathways involved in inflammatory diseases, enabling the development of targeted therapies for conditions like ulcerative colitis and Crohn's disease.
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How does the Fab format benefit applications in research?
A: The Fab format, being smaller than full antibodies, allows better tissue penetration and minimizes steric hindrance in assays. This enhances the binding efficiency and makes it ideal for research that requires detailed tissue and cellular analyses.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone mAb ACT-1"
See other products for "α4β7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-746 | Mouse Anti-α4β7 Recombinant Antibody (PABL-746) | FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-739 | Mouse Anti-α4β7 Recombinant Antibody (clone mAb ACT-1); scFv Fragment | FC | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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