How does this product contribute to inflammation research?

By targeting and elucidating the functions of α4β7, researchers can explore pathways involved in inflammatory diseases, enabling the development of targeted therapies for conditions like ulcerative colitis and Crohn's disease.

How does the Fab format benefit applications in research?

The Fab format, being smaller than full antibodies, allows better tissue penetration and minimizes steric hindrance in assays. This enhances the binding efficiency and makes it ideal for research that requires detailed tissue and cellular analyses.

Mouse Anti-α4β7 Recombinant Antibody (clone mAb ACT-1); Fab Fragment

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Product Gene Keyword

Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

See other products for "α4β7"

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IgG Antibody Products ScFv Antibody Products

CAT	Product Name	Application	Type
PABL-746	Mouse Anti-α4β7 Recombinant Antibody (PABL-746)	FC	Mouse IgG

CAT	Product Name	Application	Type
PSBL-739	Mouse Anti-α4β7 Recombinant Antibody (clone mAb ACT-1); scFv Fragment	FC	Mouse scFv

Customer Reviews and Q&As

Customer Review Q&As

Precision Tool for Immune Mapping

This Fab fragment's ability to precisely label α4β7 integrins in flow cytometry allows detailed mapping of lymphocyte trafficking. It offers high purity and specificity, which are essential for our investigations into immune cell behavior in gut tissues.

Enhanced Immune Research Insights

Utilizing this Fab fragment, we've gained enhanced insights into the roles of α4β7 in immune regulation. Its excellent tissue penetration and binding robustness are critical attributes for our cellular and molecular studies.

Q 1: How does this product contribute to inflammation research?
A: By targeting and elucidating the functions of α4β7, researchers can explore pathways involved in inflammatory diseases, enabling the development of targeted therapies for conditions like ulcerative colitis and Crohn's disease.
Q 2: How does the Fab format benefit applications in research?
A: The Fab format, being smaller than full antibodies, allows better tissue penetration and minimizes steric hindrance in assays. This enhances the binding efficiency and makes it ideal for research that requires detailed tissue and cellular analyses.

View the frequently asked questions answered by Creative Biolabs Support.