Recombinant monoclonal antibody specifically binds to Bacillus anthracis EAl protein with a high affinity (Kd = 5.81nM) , expressed in Chinese Hamster Ovary cells(CHO).
Figure 1 Cross-reactivity of monoclonal scFvs selected by competitive biopanning to Bacillus S-layer proteins by Western blot.
Love, T. E., Redmond, C., & Mayers, C. N. (2008). Real time detection of anthrax spores using highly specific anti-EA1 recombinant antibodies produced by competitive panning. Journal of immunological methods, 334(1-2), 1-10.
Figure 2 Detection of B. anthracis UM23CL2 spores on a real time biosensor using a competitively selected scFvs and a monoclonal anti EA1 antibody.
Love, T. E., Redmond, C., & Mayers, C. N. (2008). Real time detection of anthrax spores using highly specific anti-EA1 recombinant antibodies produced by competitive panning. Journal of immunological methods, 334(1-2), 1-10.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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