Mouse Anti-Bicyclooctene Recombinant Antibody (clone 39-A11) (CAT#: PABW-014)

Recombinant Mouse Antibody (39-A11) is capable of binding to Bicyclooctene hapten. The antibody catalyzes this pericyclic reaction through a combination of packing and hydrogen-bonding interactions that control the relative geometries of the bound substrates and electronic distribution in the dienophile.


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Figure 1 Binding pockets of germ-line (a), 39A11-hapten 4 complex (b), 1E9-hapten 8 complex (c), and DB3-hapten 9 complex (d) as determined by X-ray structure analysis.

Figure 1 Binding pockets of germ-line (a), 39A11-hapten 4 complex (b), 1E9-hapten 8 complex (c), and DB3-hapten 9 complex (d) as determined by X-ray structure analysis.

Electrostatic potential surfaces were constructed using residues within 16 Å of the hapten. Blue and red are positive and negative potentials, respectively.

Zhang, X., Deng, Q., Yoo, S. H., & Houk, K. N. (2002). Origins and Predictions of Stereoselective Antibody Catalysis: Theoretical Analysis of Diels− Alder Catalysis by 39A11 and Its Germ-Line Antibody. The Journal of organic chemistry, 67(25), 9043-9053.


Specifications

  • Immunogen
  • Bicyclooctene
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Tested positive against synthetic Bicyclooctene hapten
  • Clone
  • 39-A11
  • Applications
  • WB, FuncS

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Bicyclooctene

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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See other products for "Clone 39-A11"

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Fab Fragment Antibody

CAT Product Name Application Type
PFBW-014 Mouse Anti-Bicyclooctene Recombinant Antibody (clone 39-A11); Fab Fragment WB, FuncS Mouse IgG

scFv Fragment Antibody

CAT Product Name Application Type
PSBW-014 Mouse Anti-Bicyclooctene Recombinant Antibody (clone 39-A11); scFv Fragment WB, FuncS Mouse scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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