Afuco™ Anti-Human CLEC4C ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-164CL
Anti-CLEC4C ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibody that bind to BDCA2 to induce death of a plasmacytoid dendritic cell, inhibit production or secretion of inflammatory cytokines and chemokines, and treat or prevent immunological disorders such as inflammatory and autoimmune conditions.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29432/60664_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29432/60664_A_9_3.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29432/60664_A_7_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29432/60664_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29432/60664_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29432/60664_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198178-CLEC4C
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-217 | Recombinant Anti-human CLEC4C Antibody | ELISA, IF, FuncS | IgG |
| HPAB-1285LY | Human Anti-CLEC4C Recombinant Antibody (HPAB-1285LY) | ELISA | Human IgG |
| HPAB-1286LY | Human Anti-CLEC4C Recombinant Antibody (HPAB-1286LY) | ELISA | Human IgG |
| HPAB-1287LY | Human Anti-CLEC4C Recombinant Antibody (HPAB-1287LY) | ELISA | Human IgG |
| VS13-YC226 | Rabbit Anti-CLEC4C Recombinant Antibody (VS13-YC226) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-217-F(E) | Recombinant Anti-human CLEC4C Antibody Fab Fragment | IP, Neut, FuncS | Fab |
| MHH-217-F(E) | Recombinant Human Anti-human CLEC4C Antibody Fab Fragment | ELISA, WB, IF, FuncS | Fab |
| HPAB-1285LY-F(E) | Human Anti-CLEC4C Recombinant Antibody; Fab Fragment (HPAB-1285LY-F(E)) | ELISA | Human Fab |
| HPAB-1286LY-F(E) | Human Anti-CLEC4C Recombinant Antibody; Fab Fragment (HPAB-1286LY-F(E)) | ELISA | Human Fab |
| HPAB-1287LY-F(E) | Human Anti-CLEC4C Recombinant Antibody; Fab Fragment (HPAB-1287LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0425CL | Mouse Anti-CLEC4C Recombinant Antibody (TAB-0425CL) | IF | Mouse IgG |
| TAB-0425CL-S(P) | Mouse Anti-CLEC4C Recombinant Antibody; scFv Fragment (TAB-0425CL-S(P)) | ELISA, IF, FuncS | Mouse scFv |
| TAB-1244CL-S(P) | Mouse Anti-CLEC4C Recombinant Antibody; scFv Fragment (TAB-1244CL-S(P)) | ELISA | Mouse scFv |
| TAB-0425CL-F(E) | Mouse Anti-CLEC4C Recombinant Antibody; Fab Fragment (TAB-0425CL-F(E)) | ELISA, IF, FuncS | Mouse Fab |
| TAB-1244CL-F(E) | Mouse Anti-CLEC4C Recombinant Antibody; Fab Fragment (TAB-1244CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0461CL | Human Anti-CLEC4C Recombinant Antibody (TAB-0461CL) | ELISA | Human IgG |
| TAB-0462CL | Human Anti-CLEC4C Recombinant Antibody (TAB-0462CL) | ELISA | Human IgG |
| TAB-0463CL | Human Anti-CLEC4C Recombinant Antibody (TAB-0463CL) | ELISA | Human IgG |
| TAB-0461CL-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (TAB-0461CL-S(P)) | ELISA | Human scFv |
| TAB-0462CL-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (TAB-0462CL-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1245CL | Human Anti-CLEC4C Recombinant Antibody (TAB-1245CL) | ELISA, Cyt | Chimeric (mouse/human) IgG |
| TAB-1245CL-S(P) | Mouse Anti-CLEC4C Recombinant Antibody; scFv Fragment (TAB-1245CL-S(P)) | ELISA | Mouse scFv |
| TAB-1245CL-F(E) | Human Anti-CLEC4C Recombinant Antibody; Fab Fragment (TAB-1245CL-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1285LY-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (HPAB-1285LY-S(P)) | ELISA | Human scFv |
| HPAB-1286LY-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (HPAB-1286LY-S(P)) | ELISA | Human scFv |
| HPAB-1287LY-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (HPAB-1287LY-S(P)) | ELISA | Human scFv |
| HPAB-1288LY-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (HPAB-1288LY-S(P)) | ELISA | Human scFv |
| HPAB-1289LY-S(P) | Human Anti-CLEC4C Recombinant Antibody; scFv Fragment (HPAB-1289LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC27 | Recombinant Anti-CLEC4C Vesicular Antibody, EV Displayed (VS-0425-YC27) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1498 | Anti-CLEC4C Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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