Recombinant monoclonal antibody to cxcl14. Clone AF730 is a sheep monoclonal antibody that can be potentially used in the treatment of diabetes.
Figure 1 An anti-mouse CXCL14-specific antibody neutralizes an activity of CXCL14 inhibiting insulin signaling.
Differentiation-induced C2C12-derived myocytes were stimulated with insulin in the presence of indicated substances and phosphorylation of Akt Ser473 was determined by western blotting.
Figure 2 Data examining whether chemotaxis of forskolin-stimulated THP-1 cells to CXCL14 is neutralized by addition of an anti-mouse CXCL14-specific antibody.
After two hours of culture, the number of cells that migrated from inside to the back of the Chemotaxicell microchamber was determined to test statistical significant difference. The graph shows average value ± standard error for each group.
Figure 3 Data examining whether chemotaxis of forskolin-stimulated C2C12 cells to CXCL14 is neutralized by addition of an anti-mouse CXCL14-specific antibody.
After six hours of culture, the number of cells that migrated from inside to the back of the microchamber was determined to test statistical significant difference. The graph shows average value ± standard error for each group.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2063MZ | Recombinant Mouse Anti-Human CXCL14 Antibody (clone NN0324-23C35) | WB | Mouse antibody |
HPAB-0159-LSX | Rat Anti-CXCL14 Recombinant Antibody (clone MAB730) | WB | Rat IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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