Mouse Anti-Collagen type II Recombinant Antibody (clone CIIC1)

CAT#: PABW-028 Autoantibody

Recombinant Mouse Antibody (CIIC1) is capable of binding to Collagen type II, expressed in Chinese Hamster Ovary cells (CHO). Monoclonal anti-collagen type II antibody CIIC1 is an arthritogenic autoantibody, which induces arthritis in mice.

Specifications

  • Immunogen
  • Mouse Collagen type II
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Mouse Collagen type II
  • Species Reactivity
  • Mouse
  • Clone
  • CIIC1
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Collagen type II
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Breast cancer biomarkers at key points during disease progression
Induces Arthritis In Mice
We used this monoclonal antibody clone CIIC1 for our autoimmune research. It is an arthritogenic autoantibody and successfully induced arthritis in our mouse models, which was crucial for our study.
Breast cancer biomarkers at key points during disease progression
Validated For ELISA and SPR
We characterized this antibody using both ELISA and Surface Plasmon Resonance. It binds specifically to Collagen type II. The binding kinetics observed in SPR were consistent with high affinity interactions.

Q&As

  1. Is this antibody arthritogenic?

    A: Yes, the monoclonal anti-collagen type II antibody CIIC1 is known to be an arthritogenic autoantibody. It is capable of inducing arthritis in mice, making it useful for autoimmune research.

  2. What species collagen does it bind?

    A: This antibody is capable of binding to Mouse Collagen type II. It has been validated for use in Enzyme-linked Immunosorbent Assay and Surface Plasmon Resonance.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

Certificate of Analysis Lookup

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