Recombinant Mouse Anti-DENV-3 Antibody (mAb 4E11) (CAT#: PABL-446)
Recombinant Mouse Antibody (mAb 4E11) is capable of binding to DENV-3 , expressed in Chinese Hamster Ovary cells (CHO). This antibody is capable of neutralizing all four serotypes, and ourudy reveals the determinants of this cross-reactivity.
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Figure 1 4E11 blocks the binding of DE296–400 to model heparan sulfate groups.
4E11 blocks the binding of DE296–400 to model heparan sulfate groups. DE: the major dengue virus envelope glycoprotein.
Thullier, P., Demangel, C., Bedouelle, H., Mégret, F., Jouan, A., Deubel, V., ... & Lafaye, P. (2001). Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism. Journal of General Virology, 82(8), 1885-1892.
Specifications
- Immunogen
- Dengue virus 3
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native DENV-3
- Species Reactivity
- DENV
- Clone
- mAb 4E11
- Applications
- WB 1:1000-1:10000
Neut Assay-depended
FuncS Assay-depended
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- Dengue virus; DENV; Flaviviridae; dengue virus 3; DENV 3; Flaviviridae
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
ScFv Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-443 | Recombinant Mouse Anti-DENV-3 Antibody Fab Fragment (PFBL-443) | WB, FuncS | Fab |
Customer Reviews and Q&As
Customer Review
Q&As
Minimal Background
One of this antibody's distinguishing qualities is its minimal background in experimental experiments. It generates clear and specific data, making analysis simple and dependable.
Good Packaging
The antibody arrived well-packaged, with all relevant information on the datasheet. The secure packaging guaranteed that the product was in perfect condition upon delivery.
Exceptional Performance
This antibody outperformed my expectations in terms of quality and performance. The constant results I get make it an extremely useful tool in my research arsenal.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABL-446, RRID: AB_3111658)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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