Recombinant Mouse Antibody (mAb 4E11) is capable of binding to DENV-3 , expressed in Chinese Hamster Ovary cells (CHO). This antibody is capable of neutralizing all four serotypes, and ourudy reveals the determinants of this cross-reactivity.
Figure 1 4E11 blocks the binding of DE296–400 to model heparan sulfate groups.
4E11 blocks the binding of DE296–400 to model heparan sulfate groups. DE: the major dengue virus envelope glycoprotein.
Thullier, P., Demangel, C., Bedouelle, H., Mégret, F., Jouan, A., Deubel, V., ... & Lafaye, P. (2001). Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism. Journal of General Virology, 82(8), 1885-1892.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-443 | Recombinant Mouse Anti-DENV-3 Antibody Fab Fragment (mAb 4E11) | WB, FuncS | Fab |
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABL-446, RRID: AB_3111658)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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