Recombinant Mouse Anti-DENV-3 Antibody (mAb 4E11) (CAT#: PABL-446)

Recombinant Mouse Antibody (mAb 4E11) is capable of binding to DENV-3 , expressed in Chinese Hamster Ovary cells (CHO). This antibody is capable of neutralizing all four serotypes, and ourudy reveals the determinants of this cross-reactivity.

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  • Tested Data
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  • MSDS
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Figure 1 4E11 blocks the binding of DE296–400 to model heparan sulfate groups.

Figure 1 4E11 blocks the binding of DE296–400 to model heparan sulfate groups.

4E11 blocks the binding of DE296–400 to model heparan sulfate groups. DE: the major dengue virus envelope glycoprotein.

Thullier, P., Demangel, C., Bedouelle, H., Mégret, F., Jouan, A., Deubel, V., ... & Lafaye, P. (2001). Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism. Journal of General Virology, 82(8), 1885-1892.


Specifications

  • Immunogen
  • Dengue virus 3
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native DENV-3
  • Species Reactivity
  • DENV
  • Clone
  • mAb 4E11
  • Applications
  • WB 1:1000-1:10000
    Neut Assay-depended
    FuncS Assay-depended

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • Assay-depended

Target

  • Alternative Names
  • Dengue virus; DENV; Flaviviridae; dengue virus 3; DENV 3; Flaviviridae

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Fab Fragment Antibody scFv Fragment Antibody Recombinant Antibody
CAT Product Name Application Type
PFBL-443 Recombinant Mouse Anti-DENV-3 Antibody Fab Fragment (mAb 4E11) WB, FuncS Fab

Customer Reviews and Q&As

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  • Minimal Background
    One of this antibody's distinguishing qualities is its minimal background in experimental experiments. It generates clear and specific data, making analysis simple and dependable.
  • Good Packaging
    The antibody arrived well-packaged, with all relevant information on the datasheet. The secure packaging guaranteed that the product was in perfect condition upon delivery.
  • Exceptional Performance
    This antibody outperformed my expectations in terms of quality and performance. The constant results I get make it an extremely useful tool in my research arsenal.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# PABL-446, RRID: AB_3111658)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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