Afuco™ Anti-Human ESR2 ADCC Recombinant Antibody (Mayo MC10), ADCC Enhanced
CAT#: AFC-237CL
Anti-ESR2 ADCC Enhanced Antibody (Mayo MC10) is an ADCC enhanced antibody produced by our Afuco™ platform. The use of the MC10 antibody, in combination with highly specific antibodies targeting only full-length ERα, is likely to provide additional discriminatory features in breast cancers that may be useful in predicting response to therapy.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Breast Cancer
Product Property
- Purity
- >95% by HPLC
- Storage
- Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "ESR2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1845z | Mouse Anti-ESR2 Recombinant Antibody (clone 35B10) | WB, FC, IF, IHC | Mouse IgG2a |
| MOB-1335MZ | Recombinant Mouse Anti-Human ESR2 Antibody (clone 3F3) | WB | Mouse antibody |
| MRO-0555-CN | Rabbit Anti-ESR2 Recombinant Antibody (clone CBACN-220) | WB | Rabbit IgG |
| ZG-0027C | Mouse Anti-ESR2 Recombinant Antibody (clone PT0318) | IHC-P, IF, WB | Mouse IgG |
| VS3-QX391 | Mouse Anti-ESR2 Recombinant Antibody (clone 555CT18.5.5) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-249CL | Human Anti-ESR2 Recombinant Antibody (TAB-249CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1202 | Hi-Affi™ Rabbit Anti-ESR2 Recombinant Antibody (clone DS1202AB) | ICC, IF, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY188 | Mouse Anti-NHP ESR2 Recombinant Antibody (clone PGP5/10) | WB, IF, FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2369 | Anti-ESR2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2370 | Anti-Mouse ESR2 Immunohistochemistry Kit | IHC |
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