Afuco™ Anti-Human ESR2 ADCC Recombinant Antibody (Mayo MC10), ADCC Enhanced (CAT#: AFC-237CL)
Anti-ESR2 ADCC Enhanced Antibody (Mayo MC10) is an ADCC enhanced antibody produced by our Afuco™ platform. The use of the MC10 antibody, in combination with highly specific antibodies targeting only full-length ERα, is likely to provide additional discriminatory features in breast cancers that may be useful in predicting response to therapy.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Breast Cancer
Product Property
- Purity
- >95% by HPLC
- Storage
- Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- ESR2; estrogen receptor 2 (ER beta); Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; estrogen receptor beta; estrogen receptor beta 4; nuclear receptor subfamily 3 group A member 2
- Gene ID
- 2100
- UniProt ID
- F1D8N3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1845z | Mouse Anti-ESR2 Recombinant Antibody (clone 35B10) | WB, FC, IF, IHC | Mouse IgG2a |
| ZG-0027C | Mouse Anti-ESR2 Recombinant Antibody (clone PT0318) | IHC-P, IF, WB | Mouse IgG |
| VS3-QX391 | Mouse Anti-ESR2 Recombinant Antibody (clone 555CT18.5.5) | WB | Mouse IgG1 |
| VS3-WK1083 | Rabbit Anti-ESR2 Recombinant Antibody (VS3-WK1083) | WB | Rabbit IgG |
| VS3-XY3350 | Rabbit Anti-ESR2 Recombinant Antibody (clone R04-2G5) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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