Mouse Anti-GDNF Recombinant Antibody (clone CBL065) (CAT#: NEUT-870CQ)
This antibody is a mouse monoclonal antibody that binds specifically to GDNF, and it can neutralize the bioactivity of GDNF.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70283/1559_E8_4_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70283/1559_E8_4_selected.jpg
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_B_9_8_selected.jpg
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_B_9_8_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_B_7_5.jpg
Figure 4 Caudate
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_B_9_7.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_B_9_7.jpg
Figure 5 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_A_8_5.jpg
Figure 6 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_A_5_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5210/161528_A_5_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (hTEC/SVTERT24-B, SuSa, U-87 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168621-GDNF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168621-GDNF
Specifications
- Immunogen
- Recombinant protein corresponding to human GDNF
- Host Species
- Mouse
- Type
- Mouse IgG2
- Specificity
- Human GDNF
- Species Reactivity
- Human
- Clone
- CBL065
- Applications
- Neut, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Protein G affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- GDNF; glial cell derived neurotrophic factor; ATF; ATF1; ATF2; HSCR3; HFB1-GDNF
- Gene ID
- 2668
- UniProt ID
- P39905
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GDNF"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1938z | Mouse Anti-GDNF Recombinant Antibody (clone 18H1) | WB, ICC, IF, IHC | Mouse IgG1 |
| MOB-2042MZ | Recombinant Mouse Anti-Human GDNF Antibody (clone NN0409-23G0) | Neut, WB | Mouse antibody |
| MRO-0643-CN | Rabbit Anti-GDNF Recombinant Antibody (clone JA93-10) | WB, FC | Rabbit IgG |
| ZG-0685J | Rabbit Anti-GDNF Recombinant Antibody (clone 11D2) | ELISA, WB, IHC, FC, IP | Rabbit IgG |
| VS-0723-WK74 | Human Anti-GDNF Recombinant Antibody (VS-0723-WK74) | FC | Chimeric (rabbit/human) IgG1 |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0859MZ | Chicken Anti-GDNF Polyclonal IgY | ELISA, IHC, WB | Chicken antibody |
| BRD-0922MZ | Chicken Anti-GDNF Polyclonal IgY | ELISA, WB | Chicken antibody |
| BRD-1150MZ | Chicken Anti-Human GDNF Polyclonal IgY | ELISA, WB, IHC | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-871CQ | Mouse Anti-GDNF Recombinant Antibody (clone CBL442) | ELISA, WB, Neut | Mouse IgG1 |
| NEUT-872CQ | Mouse Anti-GDNF Recombinant Antibody (clone MM0308-12F9) | Neut, WB | Mouse IgG2 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1425 | Hi-Affi™ Rabbit Anti-GDNF Recombinant Antibody (clone DS1425AB) | WB, FC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for NEUT-870CQ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.