Anti-Human GLG1 Recombinant Antibody Fab Fragment
CAT#: TAB-0609CLV-F(E)
The glucagon-specific antibody is linked to a GLP-1 which results in a GLP-1 compound/glucagon antibody, the antibody have glucagon neutralizing activity and the compound can be used in the treatment of diabetes, impaired glucose tolerance, insulin resistance, various lipid disorders, obesity, cardiovascular disease and bone disorders.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong dot like cytoplasmic positivity in trophoblastic and decidual cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/50_B1_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/26308_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/26308_A_8_3.jpg
Normal Tissue
Figure 6 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/26308_A_7_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/26308_A_7_5.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10815/26308_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090863-GLG1
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Specifications
- Host Species
- Human
- Specificity
- Human
- Related Disease
- Metabolic disorder, diabete, impaired glucose tolerance, insulin resistance, various lipid disorders, obesity, cardiovascular disease, bone disorders
Target
- Alternative Names
- Glucagon-like peptide 1; GLP-1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "GLG1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2545z | Mouse Anti-GLG1 Recombinant Antibody (clone 38A11) | WB, FC, ICC, IF, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-315CL | Human Anti-GLG1 Recombinant Antibody (TAB-315CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0608CLV | Mouse Anti-GLG1 Recombinant Antibody (TAB-0608CLV) | ELISA | Mouse IgG2, κ |
| TAB-0608CLV-F(E) | Mouse Anti-GLG1 Recombinant Antibody; Fab Fragment (TAB-0608CLV-F(E)) | ELISA | Mouse Fab |
| TAB-0608CLV-S(P) | Mouse Anti-GLG1 Recombinant Antibody; scFv Fragment (TAB-0608CLV-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4450 | PE-A*01:01/Human GLG1 (SSECQGEML) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC323 | Recombinant Anti-GLG1 Vesicular Antibody, EV Displayed (VS-0425-YC323) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2821 | Anti-GLG1 Immunohistochemistry Kit | IHC |
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