Recombinant Anti-HCV NS3 Intrabody [Tat]
CAT#: IAB-B038(T)
Recombinant anti-HCV NS3 intrabody in fusion with HIV Tat works within cells and is directed against HCV NS3, expressed in E. coli cells.
Specifications
- Immunogen
- hepatitis C virus nonstructural-protein NS3
- Host Species
- mouse
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- HCV
- Applications
- Formats of immunological tests: Coimmunopricipation; Functional studies
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- HCV NS3; Hepacivirin; Hepatitis C virus NS3; Hepatitis C virus NS3 protein, genotype 2c; NS3P; p70
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "HCV NS3"
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|---|---|---|---|
| MOB-447-F(E) | Recombinant Anti-HCV NS-3 Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
| MHH-447-F(E) | Recombinant Human Anti-HCV NS-3 Antibody Fab Fragment | ELISA, WB, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MOB-447-S(P) | Recombinant Anti-HCV NS-3 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B038(A) | Recombinant Anti-HCV NS3 Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
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| CAT | Product Name | Application | Type |
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| MRO-693CQ | Recombinant Mouse Anti-HCV NS3 Antibody (MRO-693CQ) | ELISA, WB, IF | Mouse antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-484LC | Anti-HCV NS3 Recombinant Antibody (NS3-2E12) | ELISA | Mouse antibody |
| MRO-484LC-S(P) | Anti-HCV NS3 Recombinant Antibody scFv Fragment (NS3-2E12) | ELISA | Mouse antibody |
| MRO-484LC-F(E) | Anti-HCV NS3 Recombinant Antibody Fab Fragment (NS3-2E12) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
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