Anti-HIV-1-MN gp120 Recombinant Antibody (F58) (CAT#: MRO-121LC)
This product is a recombinant mouse anti-HIV-1-MN monoclonal antibody. F58 specifically binds to gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.
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Neut
Figure 1. Neutralization of HIV-1 IIIB by alanine-substituted F58 MicroAb.
Virus incubated with each MicroAb for 1 h at 37 6C was inoculated on to C8166 cells to determine the reduction in virus infectivity.
Heap, C. J., Wang, Y., Pinheiro, T. J., Reading, S. A., Jennings, K. R., & Dimmock, N. J. (2005). Analysis of a 17-amino acid residue, virus-neutralizing microantibody. Journal of general virology, 86(6), 1791-1800.
Neut
Figure 2 graphically report the results of the screening by reverse transcriptase, p24, MT-2 and syncytia formation assays, respectively, of a monoclonal antibody of the invention for the ability to neutralize infection of H9 cells by live HIV-1 strains.
Neut
Figure 3 graphically report the results of the screening by reverse transcriptase, p24, MT-2 and syncytia formation assays, respectively, of a monoclonal antibody of the invention for the ability to neutralize infection of H9 cells by live HIV-1 strains.
Specifications
- Immunogen
- RP70
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- HIV-1-MN
- Clone
- F58
- Applications
- ELISA, Inhib
- Related Disease
- AIDS
Applications
- Application Notes
- The HIV-1-MN gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- Human immunodeficiency virus type 1 MN; HIV-1 MN; Envelope glycoprotein gp120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgM Antibody Products
Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-117LC | Anti-HIV-1-MN gp120 Recombinant Antibody (P7E4) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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