Anti-HIV-1-MN gp120 Recombinant Antibody (F58) (CAT#: MRO-121LC)
This product is a recombinant mouse anti-HIV-1-MN monoclonal antibody. F58 specifically binds to gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Neut
Figure 1. Neutralization of HIV-1 IIIB by alanine-substituted F58 MicroAb.
Virus incubated with each MicroAb for 1 h at 37 6C was inoculated on to C8166 cells to determine the reduction in virus infectivity.
Heap, C. J., Wang, Y., Pinheiro, T. J., Reading, S. A., Jennings, K. R., & Dimmock, N. J. (2005). Analysis of a 17-amino acid residue, virus-neutralizing microantibody. Journal of general virology, 86(6), 1791-1800.
Neut
Figure 2 graphically report the results of the screening by reverse transcriptase, p24, MT-2 and syncytia formation assays, respectively, of a monoclonal antibody of the invention for the ability to neutralize infection of H9 cells by live HIV-1 strains.
Neut
Figure 3 graphically report the results of the screening by reverse transcriptase, p24, MT-2 and syncytia formation assays, respectively, of a monoclonal antibody of the invention for the ability to neutralize infection of H9 cells by live HIV-1 strains.
Specifications
- Immunogen
- RP70
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- HIV-1-MN
- Clone
- F58
- Applications
- ELISA, Inhib
- Related Disease
- AIDS
Applications
- Application Notes
- The HIV-1-MN gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- Human immunodeficiency virus type 1 MN; HIV-1 MN; Envelope glycoprotein gp120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgM Antibody Products
Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-117LC | Anti-HIV-1-MN gp120 Recombinant Antibody (P7E4) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
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