This product is a recombinant human antibody that specifically binds to hepcidin and regulates iron homeostasis. The antibody binds hepcidin-25 rapidly and with high affinity and dissociates from hepcidin-25 slowly with low pM dissociation constants. The epitope for the mAb is the N-terminal 9 amino acids of which are essential for hepcidin-25 binding to the iron transporter and receptor, ferroportin, and its ability to internalize and degrade ferroportin.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-506 | Human Anti-Hepcidin Recombinant Antibody (clone 8FAB) | WB, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-503 | Human Anti-Hepcidin Recombinant Antibody (clone 8FAB); Fab Fragment | WB, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-503 | Human Anti-Hepcidin Recombinant Antibody (clone 8FAB); scFv Fragment | WB, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-026CT | Human Anti-Hepcidin Recombinant Antibody (TAB-026CT) | ELISA, WB | Human IgG |
TAB-026CT-S(P) | Human Anti-Hepcidin Recombinant Antibody; scFv Fragment (TAB-026CT-S(P)) | ELISA, WB | Human scFv |
TAB-028CT-S(P) | Human Anti-Hepcidin Recombinant Antibody; scFv Fragment (TAB-028CT-S(P)) | WB | Human scFv |
TAB-026CT-F(E) | Human Anti-Hepcidin Recombinant Antibody; Fab Fragment (TAB-026CT-F(E)) | ELISA, WB | Human Fab |
TAB-028CT-F(E) | Human Anti-Hepcidin Recombinant Antibody; Fab Fragment (TAB-028CT-F(E)) | WB | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-027CT-S(P) | Human Anti-Hepcidin Recombinant Antibody; scFv Fragment (TAB-027CT-S(P)) | ELISA, Inhibion, FC | Humanized scFv |
TAB-027CT-F(E) | Human Anti-Hepcidin Recombinant Antibody; Fab Fragment (TAB-027CT-F(E)) | ELISA, Inhibion, FC | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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