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Recombinant Mouse anti-Human MMP15 Monoclonal antibody (EML769) (CAT#: MOB-1238CT)

Recombinant Mouse monoclonal antibody to Human MMP15, expressed in Chinese Hamster Ovary cells(CHO).


See more Engineered Antibody products for MMP15
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Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2611/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human heart muscle
Figure 2 IHC staining of human heart muscle
(Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2611/ihc_selected.jpg
Figure 3 Lymph node
Figure 3 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40390/92314_A_7_8.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40390/92314_A_9_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40390/92314_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40390/92314_A_4_6.jpg
Figure 7 Skin
Figure 7 Skin
(Fibroblasts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Keratinocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Langerhans Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40390/92314_B_7_1.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (BEWO, Hep G2, OE19, SK-BR-3, WM-115)
Figure 8 RNA cell line category: Cell line enhanced (BEWO, Hep G2, OE19, SK-BR-3, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102996-MMP15

Specifications

  • Immunogen
  • Human recombinant MMP15
  • Host Species
  • Mouse
  • Specificity
  • It recognizes human MMP15 in western blot without cross reactivity with human MMP14/16. Reactivity with MMP15 in other species has not been tested.
  • Species Reactivity
  • Human
  • Clone
  • EML769
  • Applications
  • Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; Western Blot
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • Protein G purified
  • Format
  • Liquid
  • Concentration
  • 0.2 mg/ml
  • Buffer
  • Preservative: None Constituents: PBS
  • Storage
  • Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

  • Alternative Names
  • MMP15; matrix metallopeptidase 15 (membrane-inserted); MTMMP2; SMCP-2; MT2-MMP; matrix metalloproteinase-15; MMP-15; MT2MMP; MT-MMP 2; membrane-type matrix metalloproteinase 2; membrane-type-2 matrix metalloproteinase; matrix metalloproteinase 15 (membrane-inserted);
  • Function
  • calcium ion binding; enzyme activator activity; metalloendopeptidase activity; peptidase activity; protein binding; zinc ion binding;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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