Recombinant Mouse anti-Human NOD2 Monoclonal antibody (3E0) (CAT#: MOB-0301CT)
Recombinant Mouse monoclonal antibody to Human NOD2, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54494/1709_H6_13_cr58048ddc6b121_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54494/1709_H6_13_cr58048ddc6b121_selected.jpg
Figure 2 Colon
(Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41985/92460_A_8_3.jpg
(Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41985/92460_A_8_3.jpg
Figure 3 Lymph node
(Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41985/92460_A_9_8.jpg
(Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41985/92460_A_9_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (HMC-1, T-47d, THP-1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167207-NOD2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167207-NOD2
Figure 4 RNA cell line category: Cell line enhanced (HMC-1, T-47d, THP-1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167207-NOD2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167207-NOD2
Specifications
- Immunogen
- Recombinant fragment, corresponding to amino acids 28-301 (MCS QEAFQAQRSQ LVELLVSGSL EGFESVLDWL LSWEVLSWED YEGFHLLGQP LSHLARRLLD TVWNKGTWAC QKLIAAAQEA QADSQSPKLH GCWDPHSLHP ARDLQSHRPA IVRRLHSHVE NMLDLAWERG FVSQYECDEI RLPIFTPSQR ARRLLDLATV KANGLAAFLL QHVQE
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 3E0
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; Immunoprecipitation; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Immunogen affinity purified
- Format
- Liquid
- Concentration
- 2.25 mg/ml
- Buffer
- Preservative: 0.05% Sodium Azide Constituents: Tris glycine, 150mM Sodium chloride
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- NOD2; nucleotide-binding oligomerization domain containing 2; CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1; nucleotide-binding oligomerization domain-containing protein 2; NOD-like receptor C2; NLR family, CARD domain containing 2; inflammatory bowel disease protein 1; caspase recruitment domain protein 15; nucleotide-binding oligomerization domain 2; caspase recruitment domain family, member 15; caspase recruitment domain-containing protein 15; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2;
- Gene ID
- 64127
- UniProt ID
- Q9HC29
- Protein Refseq
- NP_071445
- Function
- ATP binding; CARD domain binding; enzyme binding; muramyl dipeptide binding; nucleotide binding; peptidoglycan binding; protein binding; protein kinase binding;
Related Resources
NLR Signaling Pathway
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1306z | Mouse Anti-NOD2 Recombinant Antibody (clone 19A10) | WB, FC, ICC, IF, IHC, IP | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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