Recombinant Mouse anti-Human PLD2 Monoclonal antibody (EML2191)
CAT#: MOB-0173CT
Recombinant Mouse monoclonal antibody to Human PLD2, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13397/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13397/41684_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13397/41684_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13397/41684_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13397/41684_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13397/41684_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000129219-PLD2/subcellular
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Specifications
- Immunogen
- Recombinant fragment: LRDPICDDFF QLWQDMAESN ANIYEQIFRC LPSNATRSLR TLREYVAVEP LATVSPPLAR SELTQVQGHL VHFPLKFLED ESLLPPLGSK EGMIPLEVWT , corresponding to amino acids 834-934 of Human Phospholipase D2
- Host Species
- Mouse
- Antibody Isotype
- IgG2a
- Species Reactivity
- Human
- Clone
- EML2191
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- Batch dependent within range:0.36 -0.36 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PLD2; phospholipase D2; PLD1C; hPLD2; choline phosphatase 2; phosphatidylcholine-hydrolyzing phospholipase D2;
- Gene ID
- 5338
- UniProt ID
- O14939
- Protein Refseq
- NP_001230037
- Function
- NAPE-specific phospholipase D activity; hydrolase activity; phosphatidylinositol binding; phospholipase D activity; protein binding; protein kinase C binding;
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Related Signaling Pathways
Ras Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PLD2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-0425-WR632 | Mouse Anti-PLD2 Recombinant Antibody (clone 7E4D9) | IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-0425-WR633 | Mouse Anti-PLD2 Recombinant Antibody (clone 8G1G2) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5471 | Anti-PLD2 Immunohistochemistry Kit | IHC |
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