Anti-Human IL-12p40 Recombinant Antibody (c16E7) (CAT#: TAB-088ZJ)
Recombinant monoclonal antibody to interleukin 12 p40. c16E7 is a chimeric (human/mouse) antibody that can be potentially used in the treatment of crohn disease and autoimmune.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Figure 1 c6F6 and h6F6 demonstrate potent inhibition of IL-12 induced IFNγ production by NK cells relative to an IL-12Rβ1 inhibitory antibody c16E7.
Clarke, A. W., Poulton, L., Wai, H. Y., Walker, S. A., Victor, S. D., Domagala, T., ... & Doyle, A. G. (2010, September). A novel class of anti-IL-12p40 antibodies: Potent neutralization via inhibition of IL-12–IL-12Rβ2 and IL-23–IL-23R. In MAbs (Vol. 2, No. 5, pp. 539-549). Taylor & Francis.
Specifications
- Host Species
- Human
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- c16E7
- Applications
- Inhib, ELISA
- Related Disease
- Crohn disease, Autoimmune
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- IL12B; interleukin 12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; IL12, subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor; 40 kD subunit; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Gene ID
- 3593
- UniProt ID
- P29460
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Mouse Antibody Products
Humanized Antibody Products
Chimeric Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018ZJ | Anti-Human IL-12p40 Recombinant Antibody (m6F6) | Inhib, ELISA | |
| TAB-018ZJ-S(P) | Anti-Human IL-12p40 Recombinant Antibody scFv Fragment (m6F6) | ELISA | |
| TAB-019ZJ-S(P) | Mouse Anti-IL-12p40 Recombinant Antibody; scFv Fragment (TAB-019ZJ-S(P)) | ELISA, Neut | Mouse scFv |
| TAB-018ZJ-F(E) | Anti-Human IL-12p40 Recombinant Antibody Fab Fragment (m6F6) | ELISA | |
| TAB-019ZJ-F(E) | Mouse Anti-IL-12p40 Recombinant Antibody; Fab Fragment (TAB-019ZJ-F(E)) | ELISA, Neut | Mouse Fab |
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