Afuco™ Anti-Human KIR3DL2 ADCC Recombinant Antibody (IPH41), ADCC Enhanced (CAT#: AFC-449CL)
Anti-KIR3DL2 ADCC Enhanced Antibody (IPH41) is an ADCC enhanced antibody produced by our Afuco™ platform. IPH41 is a humanized cytotoxic antibody (IgG1) which targets and destroys cells expressing KIR3DL2. KIR3DL2 is an inhibitory receptor of the KIR family, normally expressed on a fraction of normal NK cells but specifically expressed in most subtypes of the orphan indication of cutaneous T-cell lymphomas (CTCL). CTCL is a group of rare cutaneous lymphomas of T lymphocytes with poor prognosis and few therapeutic options at advanced stages.
Specific Inquiry
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cutaneous Lymphoma
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- KIR3DL2; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2; p140; NKAT4; CD158K; NKAT-4; NKAT4B; killer cell immunoglobulin-like receptor 3DL2; KIR antigen 3DL2; killer Ig receptor; p70 NK receptor CL-5; MHC class I NK cell receptor; CD158 antigen-like family member K; p70 killer cell inhibitory receptor; natural killer-associated transcript 4; p70 natural killer cell receptor clone CL-5
- Gene ID
- 3812
- UniProt ID
- P43630
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
Humanized Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2182z | Mouse Anti-KIR3DL2 Recombinant Antibody (clone 36A8) | FC | Mouse IgG1 |
| HPAB-0119-LSX | Mouse Anti-KIR3DL2 Recombinant Antibody (HPAB-0119-LSX) | FC | Mouse IgG |
| HPAB-0120-LSX | Human Anti-KIR3DL2 Recombinant Antibody (HPAB-0120-LSX) | FC, FuncS | Chimeric (mouse/human) IgG1, κ |
| HPAB-J0149-YC | Mouse Anti-KIR3DL2 Recombinant Antibody (HPAB-J0149-YC) | FC, ELISA, FuncS | Mouse IgG2a, κ |
| HPAB-J0150-YC | Mouse Anti-KIR3DL2 Recombinant Antibody (HPAB-J0150-YC) | FC, ELISA, FuncS | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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