Anti-Human NPW Recombinant Antibody (5E6-C3) (CAT#: TAB-576MZ)
The antibody specifically reacts with a partial peptide at the N-terminal region or the C-terminal region of NPW, which enables to quantify NPW with highly sensitivity and specifically as well as has an excellent activity of neutralizing NPW. It is useful as an agent for preventing and treating infertility, renal edema, digestive ulcer, gastric hyperacidity, and a diagnostic for these diseases.
Specific Inquiry
Inhib
Figure 1 shows binding inhibition by peptide-1, human NPW23 or human NPW30 against the binding of monoclonal antibody 5E6-C3 to biotin-labeled peptide-1.
In the figure, -∘- (-open circle-) represents the case where peptide-1 is added, -□- (-open square-) represents the case where human NPW23 is added, and -Δ- (-open triangle-) represents the case where human NPW30 is added, respectively.
Inhib
Figure 2 shows suppression of the cAMP synthesis inhibiting activity of human NPW23 by the monoclonal antibody recognizing the amino terminus of NPW.
The case wherein it was added to human GPR7-expressed cells is shown.
Specifications
- Immunogen
- Human NPW23
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 5E6-C3
- Applications
- Inhib
- Related Disease
- Infertility, renal edema, digestive ulcer, gastric hyperacidity
Applications
- Application Notes
- This antibody has been reported for use in Inhibition.
Target
- Alternative Names
- NPW; neuropeptide W; L8; L8C; PPL8; PPNPW; hPPL8; preproprotein L8; prepro-neuropeptide W
- Gene ID
- 283869
- UniProt ID
- Q8N729
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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