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PADI2
Anti-Rat Padi2 Recombinant Antibody Fab Fragment (mAb#6)

Anti-Rat Padi2 Recombinant Antibody Fab Fragment (mAb#6) (CAT#: TAB-0921CL-F(E))

Name: Anti-Rat Padi2 Recombinant Antibody Fab Fragment (mAb#6)
SKU: TAB-0921CL-F(E)
Rating: 5 (1 reviews)

This antibody can be potentially used in the treatment of autoimmune diseases characterized by extracellular citrullination, such as rheumatoid arthritis (RA). It can strongly cross-reacts with human PAD2.

Published Data
Gene Expression
Datasheet
MSDS
COA

Figure 1 Inhibitory capacity of anti-PAD2 mAbs. The ability of selected anti-PAD2 mAbs to inhibit citrullination of fibrinogen was tested using human recombinant PAD2 (hrPAD2) as catalyst.

Figure 1 Inhibitory capacity of anti-PAD2 mAbs. The ability of selected anti-PAD2 mAbs to inhibit citrullination of fibrinogen was tested using human recombinant PAD2 (hrPAD2) as catalyst.

Test of the inhibitory capacity of mAbs #6, #8 and #10. Anti-C4 was used as control.

Normal Tissue

Figure 1 Cerebral cortex
(Glial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47735/138688_B_8_5.jpg

Figure 2 Salivary gland
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47735/138688_B_1_1.jpg

Figure 3 Colon
(Endocrine cells
Staining:Medium
Intensity: Moderate
Enterocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Enterocytes - Microvilli
Staining:Medium
Intensity: Moderate
Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47735/138688_A_9_3.jpg

Figure 4 Kidney
(Collecting ducts
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47735/138688_A_8_5.jpg

Figure 5 Testis
(Elongated or late spermatids
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47735/138688_A_5_6.jpg

RNA Expression

Figure 6 RNA cell line category: Cell line enhanced (A549, RPTEC TERT1, SK-BR-3, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117115-PADI2

Datasheet

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Host Species
Mouse

Specificity
Rat

Species Reactivity
Human

Clone
mAb#6

Applications
ELISA, WB, Inhib

Related Disease
Autoimmune diseases such as rheumatoid arthritis (RA)

Applications

Application Notes
The antibody was validated for Inhibition. For details, refer to Published Data.

Target

Alternative Names
Padi2; peptidyl arginine deiminase 2; Pdi2

Gene ID
29511

UniProt ID
P20717

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CAT	Product Name	Application
TAB-0920CL	Anti-Rat Padi2 Recombinant Antibody (mAb#2)	ELISA, SDS-PAGE, WB
TAB-0921CL	Anti-Rat Padi2 Recombinant Antibody (mAb#6)	ELISA, SDS-PAGE, WB
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CAT	Product Name	Application	Type
HPAB-0049-LS-F(E)	Mouse Anti-PADI2 Recombinant Antibody (clone mAb #2); Fab Fragment	WB, ELISA	Mouse Fab
HPAB-0050-LS-F(E)	Mouse Anti-PADI2 Recombinant Antibody (clone mAb #6); Fab Fragment	WB, ELISA	Mouse Fab
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HPAB-0049-LS-S(P)	Mouse Anti-PADI2 Recombinant Antibody (clone mAb #2); scFv Fragment	WB, ELISA	Mouse scFv
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