Recombinant Mouse Anti-VACV A33R Antibody (A2C7)
CAT#: PABC-241
Recombinant Mouse Antibody (A2C7) is capable of binding to VACV A33R, expressed in Chinese Hamster Ovary cells (CHO). A2C7 anti-A33 MAbs at 10 μg/ml exhibited strong complement-mediated EEV neutralization in the presence of complement.
Published Data
Neut
Figure 1 Mouse Anti-VACV A33R Antibody (A2C7) in Neut.
Complement and isotype dependence of anti-A33 MAb neutralization of VACV EEV. VACV EEV neutralization activity of purified anti-A33 MAbs in the absence (MAbs) or presence (MAbs+10% C´) of complement.
Matho, M. H., Schlossman, A., Meng, X., Benhnia, M. R. E. I., Kaever, T., Buller, M., ... & Zajonc, D. M. (2015). Structural and functional characterization of anti-A33 antibodies reveal a potent cross-species orthopoxviruses neutralizer. PLoS pathogens, 11(9), e1005148.
Neut
Figure 2 Mouse Anti-VACV A33R Antibody (A2C7) in Neut.
Protection of Balb/c mice from VACVWR by anti-A33 mAbs. Antibody protection against weight loss and mortality caused by VACVWR challenge. All analyzed anti-A33 MAbs protect both against weight loss and death.
Matho, M. H., Schlossman, A., Meng, X., Benhnia, M. R. E. I., Kaever, T., Buller, M., ... & Zajonc, D. M. (2015). Structural and functional characterization of anti-A33 antibodies reveal a potent cross-species orthopoxviruses neutralizer. PLoS pathogens, 11(9), e1005148.
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Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native VACV A33R
- Species Reactivity
- VACV
- Clone
- A2C7
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay, Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- A33R; VACV152; Vaccinia virus; VACV
- UniProt ID
- Q71TT1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-461 | Recombinant Mouse Anti-EEV A33R Antibody (A20G2) | WB, ELISA, FuncS | IgG |
| PABC-239 | Recombinant Mouse Anti-VACV A33R Antibody (A27D7) | ELISA, Neut | IgG |
| PABC-240 | Recombinant Mouse Anti-VACV A33R Antibody (A20G2) | ELISA, Neut | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-458 | Recombinant Mouse Anti-EEV A33R Antibody Fab Fragment (A20G2) | WB, ELISA, FuncS | Fab |
| PSBC-239 | Recombinant Mouse Anti-VACV A33R Antibody scFv Fragment (A27D7) | ELISA, Neut | scFv |
| PSBC-240 | Recombinant Mouse Anti-VACV A33R Antibody scFv Fragment (A20G2) | ELISA, Neut | scFv |
| PSBC-241 | Recombinant Mouse Anti-VACV A33R Antibody scFv Fragment (A2C7) | ELISA, Neut | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-458 | Recombinant Mouse Anti-EEV A33R Antibody scFv Fragment (A20G2) | WB, ELISA, FuncS | scFv |
| PFBC-239 | Recombinant Mouse Anti-VACV A33R Antibody Fab Fragment (A27D7) | ELISA, Neut | Fab |
| PFBC-240 | Recombinant Mouse Anti-VACV A33R Antibody Fab Fragment (A20G2) | ELISA, Neut | Fab |
| PFBC-241 | Recombinant Mouse Anti-VACV A33R Antibody Fab Fragment (A2C7) | ELISA, Neut | Fab |
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