Recombinant Mouse Anti-VACV A33R Antibody (A2C7) (CAT#: PABC-241)
Recombinant Mouse Antibody (A2C7) is capable of binding to VACV A33R, expressed in Chinese Hamster Ovary cells (CHO). A2C7 anti-A33 MAbs at 10 μg/ml exhibited strong complement-mediated EEV neutralization in the presence of complement.
Specific Inquiry
Neut
Figure 1 Mouse Anti-VACV A33R Antibody (A2C7) in Neut.
Complement and isotype dependence of anti-A33 MAb neutralization of VACV EEV. VACV EEV neutralization activity of purified anti-A33 MAbs in the absence (MAbs) or presence (MAbs+10% C´) of complement.
Matho, M. H., Schlossman, A., Meng, X., Benhnia, M. R. E. I., Kaever, T., Buller, M., ... & Zajonc, D. M. (2015). Structural and functional characterization of anti-A33 antibodies reveal a potent cross-species orthopoxviruses neutralizer. PLoS pathogens, 11(9), e1005148.
Neut
Figure 2 Mouse Anti-VACV A33R Antibody (A2C7) in Neut.
Protection of Balb/c mice from VACVWR by anti-A33 mAbs. Antibody protection against weight loss and mortality caused by VACVWR challenge. All analyzed anti-A33 MAbs protect both against weight loss and death.
Matho, M. H., Schlossman, A., Meng, X., Benhnia, M. R. E. I., Kaever, T., Buller, M., ... & Zajonc, D. M. (2015). Structural and functional characterization of anti-A33 antibodies reveal a potent cross-species orthopoxviruses neutralizer. PLoS pathogens, 11(9), e1005148.
Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native VACV A33R
- Species Reactivity
- VACV
- Clone
- A2C7
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay, Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- A33R; VACV152; Vaccinia virus; VACV
- UniProt ID
- Q71TT1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-461 | Recombinant Mouse Anti-EEV A33R Antibody (A20G2) | WB, ELISA, FuncS | IgG |
| PABC-239 | Recombinant Mouse Anti-VACV A33R Antibody (A27D7) | ELISA, Neut | IgG |
| PABC-240 | Recombinant Mouse Anti-VACV A33R Antibody (A20G2) | ELISA, Neut | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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