BV421-B*35:01/Human CYP2C18 (KPIVVLHGY) MHC Tetramer (CAT#: MHC-LC1339)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CYP2C18-derived peptide of KPIVVLHGY covering 72-80 and B*35:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000108242-CYP2C18
Specifications
- Allele
- B*35:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- CYP2C18
- Antigen Species
- Human
- Peptide
- KPIVVLHGY
- Range
- 72-80
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- CYP2C18; cytochrome P450 family 2 subfamily C member 18; CPCI; CYP2C; CYP2C17; P450IIC17; P450-6B/29C
- Gene ID
- 1562
- UniProt ID
- P33260
Downloads
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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